Secrin 2mg | 10pcs | Glimepiride | Type 2 Diabetes | ePharma
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Secrin 2mg Tablet 10pcs

Generic: Glimepiride

Type: Tablet

Pack Size: 10 Pcs

Glimepiride is used in people with type 2 diabetes to minimize elevated blood sugar levels with a balanced diet and exercise in combination.


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Discount Price: ৳ 93
MRP: ৳ 100 7% Off

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✅ Description:

  • Secrin 2mg Tablet is a medication used for treating type 2 diabetes mellitus in adults. 
  • It falls under the class of sulfonylureas and aids in regulating blood sugar levels to prevent severe complications associated with diabetes.
  • Whether used alone or in combination with other medications, Secrin 2 is typically taken just before or with the first meal of the day. 
  • Regular intake is essential for optimal benefits. Lifestyle factors such as a healthy diet, regular exercise, and weight management are crucial components of diabetes control.

Safety Advices


Alcohol
UNSAFE

Not recommended to take Secrin 2mg Tablet with alcohol. Alcohol intake may increase or decrease the blood sugar-lowering action of Secrin 2mg Tablet in an unpredictable way, resulting in a harmful event.


Pregnancy
CONSULT YOUR DOCTOR

Secrin 2mg Tablet is a pregnancy Category C medicine, indicating that there are no well-controlled studies conducted on pregnant women. If you are taking GLIMEPIRIDE during pregnancy, stop taking it at least 2 weeks before your due date or as prescribed by your doctor.


Breastfeeding
CONSULT YOUR DOCTOR

Not recommended to be taken by breastfeeding mothers. Secrin 2mg Tablet may pass into breast milk and may pose the risk of low blood sugar in the infant. Consult your doctor for further advice.


Driving
CAUTION

Not recommended in patients with fluctuating glucose levels. Glimepiride can reduce the ability to concentrate or react if your blood sugar is lowered (hypoglycemia) or raised (hyperglycemia) or if you develop visual problems as a result of such conditions. Thus, it is not recommended as the patient can endanger himself or others (e.g. when driving a car or using machines).


Kidney
CONSULT YOUR DOCTOR

Not recommended in patients with kidney dysfunction. A patient should consult a doctor before taking GLIMEPIRIDE as it may cause kidney damage.


Liver
CAUTION

Not recommended in patients with liver dysfunction. A patient should consult a doctor before taking Glimepiride as it may cause liver damage.

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✔️ Uses of Secrin 2mg Tablet
  • Type 2 Diabetes
✔️ How does Secrin 2mg Tablet work?

Secrin 2mg Tablet acts as an antidiabetic medication by increasing the release of insulin from the pancreas, thereby lowering blood glucose levels.

✔️ Side Effects of Secrin 2mg Tablet

Hypoglycemia, headache, nausea, dizziness. Rare: Allergic skin reactions, cholestasis, elevation of liver enzyme levels.

✔️ Quick Suggestions:
  • Take shortly before or with the first main meal of the day, typically breakfast. Avoid skipping meals.
  • Exercise regularly, follow a healthy diet, and take other prescribed diabetes medicines.
  • Monitor blood sugar levels regularly.
  • Be cautious while driving or operating machinery until the medication's effects are known.
  • Secrin 2 can cause hypoglycemia when used with other antidiabetic medicines, alcohol, or if meals are delayed or skipped.
  • Carry a source of glucose, like sugary food or fruit juice, to manage hypoglycemic symptoms.
  • Regularly check liver function; inform your doctor of any symptoms like abdominal pain or jaundice.
✔️ Indications:
  • Glimepiride is recommended as an adjunct to diet and exercise to lower blood glucose in patients with noninsulin-dependent (Type II) diabetes mellitus (NIDDM) when hyperglycemia cannot be controlled by diet and exercise alone.
  • Glimepiride may be used concurrently with metformin when diet, exercise, and either Glimepiride or metformin alone do not result in adequate glycemic control.
  • Glimepiride is also indicated for use in combination with insulin to lower blood glucose in patients whose hyperglycemia cannot be controlled by diet and exercise along with an oral hypoglycemic agent. Combined use of Glimepiride and insulin may increase the potential for hypoglycemia.
✔️ Pharmacology

Glimepiride is a sulfonylurea antidiabetic agent that reduces blood glucose concentration. Its primary mechanism of action involves stimulating the release of insulin from functional pancreatic beta cells. Glimepiride acts in concert with glucose by improving the sensitivity of beta cells to physiological glucose stimulation, resulting in insulin secretion. Additionally, extrapancreatic effects such as a reduction in basal hepatic glucose production, increased peripheral tissue sensitivity to insulin, and glucose uptake may also contribute to the action of Glimepiride. In non-fasting diabetic patients, the hypoglycemic activity of a single dose of Glimepiride persists for 24 hours.

✔️ Dosage & Administration:

Adult Dose:

  • Initially, 1-2 mg daily, increased in increments of 1-2 mg at intervals of 1-2 weeks. Maintenance: 4 mg daily. Max: 6 mg daily. For the elderly, initially 1 mg once daily. Severe hepatic impairment is contraindicated.

Child Dose:

  • Safety and efficacy not established.

Renal Dose:

  • Renal impairment: 1 mg PO qDay; titrate dose based on fasting blood glucose levels. Severe renal impairment is contraindicated.

Administration:

  • To be taken with food. Should be taken just before or during the first main meal of the day. Avoid skipping meals.
✔️ Interaction

Interactions that may potentiate the hypoglycemic activity of Glimepiride include ACE inhibitors, anabolic steroids, azapropazone, chloramphenicol, coumarin derivatives, fluconazole, MAO inhibitors, probenecid, quinolones, salicylates, sulfonamide antibiotics, and more. Drugs that may diminish the hypoglycemic activity include barbiturates, calcium channel blockers, corticosteroids, diazoxide, diuretics, glucagon, isoniazid, nicotinic acid, phenothiazines, rifampicin, sympathomimetic agents, thyroid hormones, and others.

✔️ Contraindications

Glimepiride is not suitable for the treatment of insulin-dependent (Type I) diabetes mellitus, diabetic ketoacidosis, or diabetic coma. It should not be used in patients allergic to Glimepiride, other sulfonylureas, other sulfonamides, severe hepatic dysfunction, severe impairment of renal function, or dialysis patients.

✔️ Pregnancy & Lactation

Glimepiride is contraindicated during pregnancy, and a transition to insulin is necessary. Breastfeeding women should not take Glimepiride as it may harm the baby. Transitioning or complete cessation of breastfeeding is necessary.

✔️ Precaution & Warnings:

Increased risk of CV mortality, monitor blood glucose concentration. Caution in the elderly, hepatic and renal impairment, and SIADH in patients with CHF or hepatic cirrhosis. Pregnancy, lactation.

✔️ Storage Conditions

Store below 30°C temperature, protected from light and moisture. Keep out of the reach of children.

Frequently Asked Questions (FAQ)

If a meal is skipped, skip the corresponding dose of Secrin 2. If an extra meal is consumed, an additional dose may be needed.

The patient is advised to talk to a doctor before taking contraceptive pills if he/she is already taking GLIMEPIRIDE, then the doctor may change the dose of GLIMEPIRIDE. This is because oral contraceptive pills change body responds to the sugar.

Avoid intake of Glimepiride and consult a doctor if you have an allergy to sulfa drugs, diabetic ketoacidosis, heart disease, liver or kidney disease, an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD).

The Secrin 2mg Tablet contains Glimepiride which acts on insulin-secreting cells called beta cells inside the pancreas and activates calcium channels on cells which lets insulin pass out of the cell. This insulin then makes each cell in the body take up glucose and utilize it, thus lowering raised blood glucose. Therefore, it prevents symptoms of type 2 diabetes.
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Check our pricing section for Secrin 2mg Tablet 10pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability:
ePharma reserves the right to make adjustments to pricing, Products and Service offerings for reasons including, but not limited to, changing market conditions, Product discontinuation, Product unavailability, manufacturer price changes, supplier price changes and errors in advertisements. All orders are subject to Product availability and the availability of Personnel to perform the Services. Therefore, Seller cannot guarantee that it will be able to fulfill Customer’s orders. If Services are being performed on a time and materials basis, any estimates provided by Seller are for planning purposes only.

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